beta propiolactone|β : Clark BPL, Hydroacrylic acid, β-lactone, 3-Hydroxy-β-lactone, 3-Hydroxy-propionic acid, β-Lactone, 2-Oxetanone, 3-Propiolactone Colorless liquid with a slightly sweet odor.
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beta propiolactone,
β-Propiolactone, often simply called propiolactone, is an organic compound with the formula CH 2 CH 2 CO 2.It is a member of the lactone family, with a four-membered ring. It is a colorless liquid with a slightly sweet odor, highly soluble in water and organic solvents. [2] [3] The carcinogenicity of this compound has limited its commercial applications.[4]Beta-propiolactone is a colorless liquid with a strong, slightly sweet odor. It may occur naturally, but no clear documentation of its occurrence in nature was found, and it must be synthesized for commercial purposes.beta-Propiolactone can cause cancer according to an independent committee of scientific and health experts. California Office of Environmental Health Hazard Assessment (OEHHA) Beta-propiolactone appears as a colorless liquid with a slightly sweetish, pungent odor.Beta-propiolactone (BPL) is the second most commonly used inactivation method for vaccine development after formaldehyde [23,26,42]. It is an alkylating agent that modifies the structure of nucleic acids forming crosslinks between DNA and proteins, and between DNA strands in the double helix ( Table 1 ) [ 52 ].
BETA-PROPIOLACTONE is an ester. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by .
BPL, Hydroacrylic acid, β-lactone, 3-Hydroxy-β-lactone, 3-Hydroxy-propionic acid, β-Lactone, 2-Oxetanone, 3-Propiolactone Colorless liquid with a slightly sweet odor.BPL, Hydroacrylic acid, β-lactone, 3-Hydroxy-β-lactone, 3-Hydroxy-propionic acid, β-Lactone, 2-Oxetanone, 3-Propiolactone Colorless liquid with a slightly sweet odor.βBPL, Hydroacrylic acid, β-lactone, 3-Hydroxy-β-lactone, 3-Hydroxy-propionic acid, β-Lactone, 2-Oxetanone, 3-Propiolactone Colorless liquid with a slightly sweet odor.beta propiolactone βBPL, Hydroacrylic acid, β-lactone, 3-Hydroxy-β-lactone, 3-Hydroxy-propionic acid, β-Lactone, 2-Oxetanone, 3-Propiolactone Colorless liquid with a slightly sweet odor.beta-Propiolactone is used for vaccines, tissue grafts, surgical instruments, and enzymes, as a sterilant of blood plasma, water, milk, and nutrient broth, and as a vapor-phase disinfectant in enclosed spaces. Its sporicidal action is used against .
beta propiolactone β-Propiolactone is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals. β-Propiolactone caused tumors in two rodent species, at several different tissue sites, and by several different routes of exposure.
beta propiolactone|β
PH0 · β
PH1 · beta
PH2 · Propiolactone
PH3 · Methods of Inactivation of Highly Pathogenic Viruses for
PH4 · CDC
PH5 · Beta
PH6 · BETA